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Cooperation, privatization and cheating in microbial exoenzyme synthesis: theoretical analysis in view of biotechnological applications

This study presents a mathematical framework for investigating the dynamics of coexistence and competition among heterotrophic microbes across different time scales. Focusing on metabolic interactions, we examine how three strategies: public metabolizing, private metabolizing, and cheating, shape population behaviour. The framework integrates generalized Lotka-Volterra dynamics with evolutionary game theory to capture the effects of resource exchange, particularly glucose made available by...

bioRxiv 10d ago

Redesigning an elusive bacterial enzyme into an efficient green catalyst

Redesigning an elusive bacterial enzyme into an efficient green catalyst Sadie Harley Scientific Editor Robert Egan Associate Editor Industrial oxidation chemistry is a cornerstone of modern manufacturing, accounting for nearly one-third of all chemical industrial processes. While essential for making pharmaceuticals, dyes, and many specialty chemicals, industrial oxidation typically relies on high-temperature, high-pressure processes involving toxic oxidizing agents. This has motivated...

Phys.org 7d ago

Genetic code expansion enables plant-directed control of bacterial activity

Programmable control of microbial gene expression by plant hosts could enable a new generation of precision agricultural biotechnology. Here, using O-methyl-L-tyrosine (OMY) as a model compound, we establish non-standard amino acids (nsAA) as a platform for plant-based control of associated microbial activity. We use genetic code expansion to engineer OMY-dependent control of protein synthesis in the soil bacterium Bacillus subtilis.

bioRxiv 11d ago

Spider webs capture hidden fungal diversity in Thai rice fields

Spider webs capture hidden fungal diversity in Thai rice fields Lisa Lock Scientific Editor Robert Egan Associate Editor A new study published in the open-access Biodiversity Data Journal suggests that spider webs—particularly those incorporating environmental debris—can serve as natural, non-destructive collectors of fungal material in agricultural ecosystems. The findings show that viable fungi can be recovered from these structures, including lineages that may represent previously...

Phys.org 6d ago

Integrated valorisation of PET and xylose using the oleaginous microorganisms Yarrowia lipolytica and Rhodococcus jostii

The increasing accumulation of polyethylene terephthalate (PET) waste has prompted the development of sustainable biotechnological strategies for its degradation and valorisation. This study presents an integrated approach combining enzymatic PET depolymerization by Yarrowia lipolytica, engineered to express and secrete the cutinase HiC and the lipase CalB, with the microbial valorization of PET-derived monomers, terephthalic acid (TPA) and ethylene glycol (EG), by Rhodococcus jostii RHA1....

bioRxiv 9d ago

DNA had one rule. Bacteria didn’t get the memo

Bacteria didn’t get the memo June 1, 2026Your DNA has never been created from scratch. Think of it like a recipe — passed down from parent to child over countless generations, all the way back 4 billion years to the earliest life on Earth. With tweaks and changes accumulating along the way, but always copied from something that already existed.

Deutsche Welle 9d ago

Lignin to adipic acid in a high-yield chemical and biological redox process

Abstract Viable manufacturing pathways to produce bio-based chemicals from renewable feedstocks, such as lignin derived from plant biomass, are needed to decarbonize the chemicals manufacturing sector. Converting the recalcitrant lignin polymer to valuable bioproducts remains a longstanding challenge in biorefining, with the highest reported single-product yield from lignin currently around 20 wt% (refs. Most existing lignin depolymerization strategies target aryl–ether bond cleavage, which...

Nature 16h ago

Study reveals hidden gut factor that may make some people more susceptible to sepsis

Potentially deadly sepsis may be more likely in certain patients due to problems in the gut. Researchers from the Korea Research Institute of Bioscience and Biotechnology's Infectious Disease Research Center used female mouse models to investigate why sepsis outcomes can vary so dramatically. The study, published in the journal Nature, looked at genetically similar mice with different gut microbiomes.

Fox News 2d ago

Compartment-Specific Assembly and Functional Potential of the Bacteriome of Citrullus colocynthis in a Semi-Arid Ecosystem

Plants inhabitng in arid and semi-arid ecosystems, such as Citrullus colocynthis (L.) Schrad., are adapted to drought, heat, salinity, and nutrient limitation. Their associated microbial communities may further support plant persistence under these harsh conditions. Here, we characterized the bacterial communities associated with leaf endosphere, rhizosphere and roots of C. colocynthis growing in a semi-arid region of Moroccan using 16S rRNA gene amplicon sequencing, culture-dependent...

bioRxiv 3d ago