Microdroplet
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Related Articles from SNS
Rapid Determination of Drug-to-Antibody Ratios in Antibody Drug Conjugates Using Ultrafast Microdroplet Digestion Technology
Accurate determination of drug to antibody ratios (DARs) is essential for the development, quality control, and performance evaluation of antibody drug conjugates (ADCs); yet conventional analytical approaches often require extensive sample preparation, long analysis time, and substantial sample consumption. The peak distribution of intact ADCs is highly complex due to inherent glycosylation heterogeneity and variable drug conjugation. By applying enzymatic digestion, ADC can be converted...
3D-printed nozzle array could streamline production of drug-delivery microparticles
3D-printed nozzle array could streamline production of drug-delivery microparticles Lisa Lock Scientific Editor Robert Egan Associate Editor MIT researchers have demonstrated a low-cost design for specialized electronic nozzles, called triaxial electrospray emitters, that could be used to manufacture time-release drug-delivery particles or self-healing materials efficiently and at scale. Triaxial electrospray emitters use electricity to precisely dispense three liquids from microscopic...
Fast-moving droplets synthesize key drug compounds at room temperature, no catalysts needed
Fast-moving droplets synthesize key drug compounds at room temperature, no catalysts needed Lisa Lock Scientific Editor Robert Egan Associate Editor Chemical reactions are the backbone to nearly all biological processes, including those used to make new medicines. However, these reactions can often take considerable time and require harsh conditions or materials—potentially inhibiting the timely development of life-changing drugs. Purdue University researcher Graham Cooks and his team at...
MIT boffins take electrospray nozzles out of the cleanroom, into the 3D printer
The process for producing triple-layer drug-delivery particles and materials for tissue regeneration could get easier, thanks to a new advance in creating the electrospray nozzles used to make them. A team of MIT researchers has now used a 3D resin printer to output tiny electrospray nozzles without the expensive cleanrooms they normally require. A team led by MIT principal research scientist Dr. Luis Fernando Velásquez-García detailed its work developing tiny arrays of triaxial electrospray...
Environmental engineers reshape understanding of airborne pollution particles
Environmental engineers reshape understanding of airborne pollution particles Gaby Clark Scientific Editor Robert Egan Associate Editor From sizzling bacon in the kitchen to wildfire smoke in the sky, cooking and pollution release microscopic particles that affect humans' health, the air they breathe, and even weather and climate. New research from Virginia Tech is poised to upend how scientists think about the structure of these tiny airborne droplets and what that means for predictions...