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Related Articles from SNS

Chronic Stress Exacerbates Long-term Microvascular Network Dysfunction Following Brain Trauma

Background: Preexisting factors are among the strongest predictors of recovery following traumatic brain injury (TBI), with chronic stress closely associated with permanent disability and worse long-term outcomes. While chronic cerebrovascular dysfunction is linked to these poor trajectories, as impaired blood flow regulation drives secondary disease progression, the mechanisms regulating this vascular failure remain incompletely understood. Crucially, how premorbid chronic stress and TBI...

bioRxiv 1d ago

Hyaluronic Acid Plays Differential Molecular Weight and Concentration Dependent Pathway Centric Changes to Human Lung Derived Microvascular Endothelial Cells in Culture

Background Hyaluronan (HA) is a major extracellular matrix glycosaminoglycan that regulates vascular integrity and immune signaling in the lung. Its biological effects are strongly size-dependent, with high-molecular-weight HA (HMW-HA) generally protective and low-molecular-weight HA (LMW-HA) pro-inflammatory. However, how different HA sizes and concentrations globally remodel endothelial cell signaling remains poorly understood.

bioRxiv 7d ago

Three-Dimensional Retinal Microvasculature Restoration in OCT Angiography

Announce Type: new Abstract: Optical coherence tomographic angiography (OCTA) is a powerful technique for imaging retinal microvasculature. However, acquiring reliable quantification of retinal blood flow and areas of retinal nonperfusion is challenging because of imaging artifacts. Existing methods primarily focus on noise suppression, projection artifact removal, or signal enhancement to improve the image quality of OCTA in cross-sectional or two-dimensional (2D) en face projections, while...

arXiv CS 5d ago