N K Singh
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Staff dismissal only for grave violations like corruption: SC
Supreme Court on Thursday said that a long-standing employee cannot be dismissed from service for indiscipline, insubordination or disobedience and such a penalty must be reserved for cases of corruption, moral turpitude or mala fide actions causing loss to the employer. A bench of Justices Sanjay Karol and N K Singh said it was not making light of the importance of discipline at the workplace, but in the absence of “corruption, illegal gratification, moral turpitude, misappropriation of...
Compassionate job & financial benefit can’t have conflicting clauses: SC
In Haryana, if a family member is accused of murdering a govt servant, then he/she or their family members are not entitled to any compassionate financial benefit till they are cleared of the criminal case, but they are eligible for compassionate employment in lieu of the deceased employee. Taking exception to this conflict, a bench of Justices Sanjay Karol and N K Singh said the incongruency in the welfare scheme is apparent as the lesser of the relief, that is the financial assistance, is...
'Homemakers are nation builders': For payout, SC pegs housewife ‘income’ at Rs 30,000 a month
Calling housewives “nation builders”, Supreme Court for the first time said in case of a homemaker’s death in an accident, the Motor Accident Claims Tribunal will calculate the compensation to be paid to her family by assuming her monthly income to be at least Rs 30,000. Pained by the 25-year delay, 22 of which were because the matter remained pending in Punjab and Haryana HC, in grant of compensation to the family of a homemaker who died in an accident on Nov 25, 2001, SC said the economy...
Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).
Whole-genome duplication shaped cell-type evolution in the vertebrate brain
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...