NIMA
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NEK kinase TcRDK2 controls differentiation, host-cell infection, and remodeling of the translation initiation machinery in Trypanosoma cruzi
Trypanosoma cruzi, the etiologic agent of Chagas disease, alternates between replicative epimastigotes and amastigotes and non-dividing, mammal-infective metacyclic and bloodstream trypomastigotes. Protein phosphorylation is a major regulatory mechanism in trypanosomatids, whose kinomes reveal an expanded family of NIMA-related kinases (NEKs). Here, we investigated the role of T. cruzi RDK2 (Repressor of Differentiation Kinase 2), a conserved NEK that carries a C-terminal pleckstrin homology...
Months after the regime crackdown, Iranians search for missing protesters
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Sherpa survives 6-day Everest ordeal sans food, O2
In what climbers are calling a miracle, a 52-year-old Sherpa guide who was presumed dead on Mount Everest after he vanished during descent on May 29 was found alive after six days near Base Camp on Thursday morning. Dawa 'Hillary' Sherpa -- who earned the moniker for his mountaineering expertise - covered more than 12km from Yellow Band (25,000ft) to Crampon Point (17,000ft) in difficult weather without food, water or supplemental oxygen, crossing the treacherous Khumbu icefall after the...