Neurology
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Integrating Mechanistic and Data-Driven Models for Neurological Disorders through Differentiable Programming
Announce Type: cross Abstract: Advances in computational modeling, neuroimaging, and artificial intelligence are revolutionizing the modeling of neurological disorders for improved diagnostics, prognosis, and treatment planning. Mechanistic models provide valuable scientific insight into the disorders, but in practice they are often simplified with assumptions or computationally expensive and slow to solve. However, while purely data driven approaches provide speed and scalability, they...
Integrating Mechanistic and Data-Driven Models for Neurological Disorders through Differentiable Programming
Announce Type: new Abstract: Advances in computational modeling, neuroimaging, and artificial intelligence are revolutionizing the modeling of neurological disorders for improved diagnostics, prognosis, and treatment planning. Mechanistic models provide valuable scientific insight into the disorders, but in practice they are often simplified with assumptions or computationally expensive and slow to solve. However, while purely data driven approaches provide speed and scalability, they...
SleepExplain: Explainable Non-Rapid Eye Movement and Rapid Eye Movement Sleep Stage Classification from EEG Signal
arXiv:2606.07351v1 Announce Type: new Abstract: Classification of sleep stages is one of the most important diagnostic approaches for a variety of sleep-related disorders. Electroencephalography (EEG) is regarded as a powerful tool for examining the association between neurological effects and sleep phases since it correctly identifies sleep-related neurological alterations. During Non-Rapid Eye Movement (NREM) and Rapid Eye Movement (REM) sleep phases, a number of nerve and bodily functions...
This exercise habit may slash dementia risk and help you live longer, study finds
People who incorporate strength training into their weekly routines may be more likely to live longer, according to a new study. Researchers from the Harvard T.H. Chan School of Public Health analyzed data from 147,374 adults and found that people who engaged in moderate amounts of resistance training had a lower risk of dying from several major causes, including heart disease and neurological disease. The findings were published in the British Journal of Sports Medicine.
Trump declared 'fully fit' for all presidential duties after annual physical shows 'excellent health'
President Donald Trump remains in "excellent health," his physician said in a memo released Friday following the president’s annual physical earlier this week. The report came after Trump underwent his annual examination Tuesday at Walter Reed National Military Medical Center. "President Donald Trump remains in excellent health, demonstrating strong cardiac, pulmonary, neurological, and overall physical function," Navy Capt. Sean P. Barbabella, the president’s physician, wrote in the memo.
Brain and neuronal expression and localization of de-S-acylating enzymes
S-acylation is a reversible posttranslational lipid modification important in the nervous system that dynamically regulates protein localization and function. Aberrant S-acylation has been implicated in several neurological conditions. While several de-S-acylases (deacylases hereafter) have been identified, little is known regarding their expression and localization in the brain and in neurons.
Combinatorial screening of nanoparticles for nose-to-brain RNA delivery to modulate neuroinflammation after traumatic brain injury
Traumatic brain injury (TBI)-induced neuroinflammation can evolve over weeks or months,contributing to ongoing secondary damage and worsening neurological recovery. RNA-based therapeutics hold great potential to regulate inflammatory signaling, but delivery to the brain remains challenging because of the blood brain barrier. Intranasal administration offers a direct non-invasive route for brain access but is often limited by low delivery efficiency.
Trump declared 'fully fit' for all presidential duties after annual physical shows 'excellent health'
President Donald Trump remains in "excellent health," his physician said in a memo released Friday following the president’s annual physical earlier this week. The report came after Trump underwent his annual examination Tuesday at Walter Reed National Military Medical Center. "President Donald Trump remains in excellent health, demonstrating strong cardiac, pulmonary, neurological, and overall physical function," Navy Capt. Sean P. Barbabella, the president’s physician, wrote in the memo.
Trump in excellent health after annual checkup, his doctor says
Trump in excellent health after annual checkup, his doctor says Donald Trump's doctor says the US president is in "excellent health" following his annual medical exam. In a memo released by the White House on Friday, Capt Sean Barbabella said Trump, who turns 80 next month, has "strong cardiac, pulmonary, neurological and overall physical function" and is "fully fit to carry out all duties of the Commander-in-Chief and Head of State". Trump visited the Walter Reed National Military Medical...
Next-Token Prediction Learns Generalisable Representations of Sleep Physiology
arXiv:2606.09605v1 Announce Type: new Abstract: Foundation models offer a promising route to compress multi-modal physiological signals into compact representations of human health, with broad applications across sleep medicine, cardiology, neurology and other healthcare domains. Existing models have typically been trained with masked-reconstruction or contrastive objectives. However, masked reconstruction may be poorly suited to the stochastic nature of these signals, while contrastive...