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4 - O'Shea Robert J (0001382617) (Reporting)
Filed: 2026-06-01 AccNo: 0001193125-26-252106 Size: 10 KB
Scientists discover a hidden quantum world inside cobalt
Scientists discover a hidden quantum world inside cobalt - Date: - June 5, 2026 - Source: - Helmholtz-Zentrum Berlin - Summary: - Scientists have uncovered unexpected quantum complexity inside cobalt, a metal long thought to be fully understood. Advanced measurements revealed a dense network of topological electronic states that remain robust at room temperature. These states enable extremely fast electron behavior and can be switched or controlled using magnetism.
Kevin O’Leary’s gargantuan data center cut down by half after battle with Utah lawmakers
Kevin O’Leary’s gargantuan data center cut down by half after battle with Utah lawmakers The data center’s campus was originally going to be twice the size of Manhattan. Now it will only be slightly larger than the island - Bookmark - CommentsGo to comments Shark Tank celebrity investor Kevin O'Leary has decided to join the data center gold rush, but Utah Senate President J. Stuart Adams is mucking up his claim. O'Leary's proposed data center — to be built in Box Elder County, Utah — is...
Gene ancestries reveal diverse microbial associations during eukaryogenesis
Abstract The origin of eukaryotes remains a central enigma in biology1. Continuing debates agree on the pivotal role of a symbiosis between an alphaproteobacterium and an Asgard archaeon2,3. However, the nature, timing and contributions of other potential bacterial partners4,5,6 and the role of interactions with viruses7,8,9 remain contentious.
Christmas Day delivers Derby victory for O'Brien
Epsom: Christmas Day delivers Derby victory for Aidan O'Brien and Ronan Whelan Navigating difficult conditions on the Epsom Downs, Christmas Day roared to Derby success - a 12th win in the race for trainer Aidan O'Brien; Maltese Cross was the best of the home team in second with James J Braddock third Saturday 6 June 2026 16:55, UK Christmas Day provided Aidan O'Brien with his 12th victory in the Betfred Derby at Epsom. The Ballydoyle handler saddled four runners in his pursuit of a dozen...
Epsom Derby tips: the runners, riders and which horse to bet on
The Epsom Derby, with its top prize of £1m, takes place on Saturday at 4pm. The favourite, Benvenuto Cellini, looks a solid bet. He stays, appears to have pace and balance and I cannot see Ryan Moore picking any of the other six Ballydoyle runners over him.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
Diverse binding poses of agonistic neurotoxins on human Na<sub>v</sub>1.6
Abstract Voltage-gated sodium (Nav) channels are key targets of various venomous toxins. Deciphering the binding poses and mechanisms of action of representative toxins will help to dissect the functional mechanism of the channels and facilitate therapeutic development targeting Nav channels1,2. Here we present cryo-electron microscopy (cryo-EM) structures of distinct binding poses of three agonistic peptide toxins on the human Nav1.6–β1 channel complex.
A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases
Abstract Nuclear receptors are central regulators of metabolism1, yet therapeutic strategies that enforce continuous receptor activation frequently lead to reduced efficacy and unacceptable toxicity. Here we report a first-principles drug design strategy that aligns pharmacokinetics with physiological signalling cycles. We developed linafexor, a potent non-bile-acid agonist of the farnesoid X receptor (FXR)2; it is engineered for rapid systemic clearance, which enables pulsatile receptor...
Deep learning four decades of human migration
Abstract Human migration is a fundamental driver of global demographic change, shaping population structure, labour markets and social policy across countries1,2,3. Although long-term migration patterns are often linked to economic development4, they can shift rapidly in response to shocks such as conflict, environmental crises and political change5. Despite its importance, migration remains difficult to measure consistently: existing data are sparse, concentrated in high-income settings and...