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Small but Mighty: The Surprising Metabolic Range of a Bacterial Microcompartment

Bacterial microcompartments (BMCs) are protein-based metabolic modules increasingly investigated as potential intracellular nanoreactors. In this study, we engineered Escherichia coli by chromosomally integrating the propanediol utilization (pdu) operon from Citrobacter freundii and evaluated the metabolic versatility of the heterologously produced Pdu BMCs. The formation of well-assembled, operational Pdu BMCs was confirmed in cellula.

bioRxiv 3d ago