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Weekly diabetes jab shown to reduce blood-sugar levels and body weight

Experts say results from trial of new triple hormone drug for type 2 diabetes are striking but further tests neededA new triple-action weekly jab for type 2 diabetes could significantly reduce blood sugar and body weight, according to phase 3 trial results. Patients in the trial receiving weekly retatrutide injections for 40 weeks lost more than four times as much weight as those on placebo, while the average drop in long-term blood sugar (HbA1c) was more than twice that of the placebo. The...

The Guardian World 3d ago

Weekly diabetes jab shown to reduce blood-sugar levels and body weight

Experts say results from trial of new triple hormone drug for type 2 diabetes are striking but further tests neededA new triple-action weekly jab for type 2 diabetes could significantly reduce blood sugar and body weight, according to phase 3 trial results. Patients in the trial receiving weekly retatrutide injections for 40 weeks lost more than four times as much weight as those on placebo, while the average drop in long-term blood sugar (HbA1c) was more than twice that of the placebo. The...

The Guardian UK 3d ago

Weekly diabetes jab shown to reduce blood-sugar levels and body weight

Experts say results from trial of new triple hormone drug for type 2 diabetes are striking but further tests neededA new triple-action weekly jab for type 2 diabetes could significantly reduce blood sugar and body weight, according to phase 3 trial results. Patients in the trial receiving weekly retatrutide injections for 40 weeks lost more than four times as much weight as those on placebo, while the average drop in long-term blood sugar (HbA1c) was more than twice that of the placebo. The...

The Guardian Health 3d ago

Retatrutide: Triple acting jab for type 2 diabetes lowers blood sugar and boosts weight loss, trial reports

Retatrutide, a triple action treatment for type 2 diabetes, could significantly reduce blood glucose concentrations and body weight in patients with the condition, a phase 3 trial has reported. The results, published in the Lancet,1 show that patients who received injections of retatrutide for 40 weeks lost more than four times as much weight as those in the placebo group. After 40 weeks the average reduction in HbA1c with the new treatment was more than twice that in the placebo group,...

BMJ (British Medical Journal) 1d ago

World's largest opioid review finds they often don't work

World's largest opioid review finds they often don't work - Date: - June 9, 2026 - Source: - University of Sydney - Summary: - The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo.

Science Daily 1d ago

Weight loss drug maker sinks 25% after new safety data spooks investors

Shares of weight loss drug maker Zealand Pharma plummeted as much as 26% on Monday after new data on its experimental medicine raised concerns over its potential side effects. The Danish drugmaker said that while its drug survodutide met its key targets in a late-stage study, 19% of patients dropped out of the study due to gastrointestinal events, compared to 2.9% on placebo. "Safety/tolerability remains the key issue," said Barclays analysts in a note on Monday.

CNBC 2d ago

Global nonequilibrium cortical dynamics tie mid-level pupil-linked arousal to optimal task performance in humans

Ongoing fluctuations in brain state, largely driven by neuromodulators of arousal, shape how sensory inputs are processed and decisions are made. Here, we combined pharmacological manipulations and pupillary proxies of arousal to examine how global cortical state dynamics relate to perceptual sensitivity. We applied the thermodynamics-inspired INSIDEOUT framework to electroencephalography (EEG) recordings from two visual discrimination tasks performed under placebo, atomoxetine...

bioRxiv 5d ago

Cancer patients found a simple way to stay mentally sharp during chemotherapy

Cancer patients found a simple way to stay mentally sharp during chemotherapy A simple exercise routine may help protect cancer patients from “chemo brain,” with researchers finding noticeable improvements in attention and cognitive function during treatment. - Date: - June 9, 2026 - Source: - Wiley - Summary: - “Chemo brain” affects up to 80% of people receiving chemotherapy, making everyday tasks harder.

Science Daily 16h ago

Repairing DNA damage: Scientists discover a surprising new benefit of melatonin

Repairing DNA damage: Scientists discover a surprising new benefit of melatonin A small clinical trial suggests melatonin supplements could help night shift workers repair DNA damage linked to working overnight. - Date: - May 30, 2026 - Source: - BMJ Group - Summary: - A new study suggests melatonin supplements may help night shift workers boost their body's DNA repair processes, potentially offsetting some of the damage linked to working overnight. The findings are early but raise the...

Science Daily 11d ago

This drug delayed rheumatoid arthritis for years after treatment ended

This drug delayed rheumatoid arthritis for years after treatment ended - Date: - June 1, 2026 - Source: - King's College London - Summary: - A promising new study suggests rheumatoid arthritis may not be as inevitable as once thought for people at high risk. Researchers found that just one year of treatment with the immune-targeting drug abatacept delayed the onset of rheumatoid arthritis by up to four years, with benefits lasting long after treatment ended. - Share: People at high risk of...

Science Daily 9d ago