Poole Harbour

Three arrested and murder investigation launched after police recover body from Poole Harbour

Police recovered the body from Poole Harbour

Murder arrests after man reported missing from boat

Three men are held on suspicion of murder after reports that a man went overboard in Poole Harbour.

First osprey chick of the year hatches

Three arrested in murder probe after man 'went overboard on sailing boat and has not been found'

Three arrested in murder probe after man 'went overboard on sailing boat and has not been found' Dorset Police have arrested three people in connection to the death of a man who was believed to have gone into the water from a sailing boat in the area of Arne Bay between around 8pm and 9pm on Friday Three people have been arrested on suspicion of murder after a man 'went overboard on sailing boat and has not been found' A 46-year-old man from Poole, a 31-year-old man of no fixed abode and a...

Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer

Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.

Ferrari make big statement in Monaco practice runs

Ferrari make big statement in Monaco practice runs MONACO, June 5 : Ferrari laid down a strong marker ahead of qualifying for the Monaco Grand Prix as Charles Leclerc and Lewis Hamilton went quickest in Friday's two free practice sessions. After five rounds of Mercedes dominance, the return to Europe on the twisty principality street circuit has been flagged as an opportunity for their rivals, with Ferrari regarded as favourites for Sunday's race. They lived up to their billing with...