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PanKbase Integrated Single-Cell Map: A Comprehensive Atlas of Human Pancreatic Islets

Abstract Aims/hypothesis Single-cell RNA sequencing (scRNA-seq) of pancreatic islet tissue is a powerful tool for investigating Type 1 Diabetes (T1D). However, individual datasets are limited in size and fragmented across donors, laboratories, and experimental conditions, highlighting the need for a unified single-cell atlas. This study aimed to construct a comprehensive, integrated scRNA-seq map of human isolated pancreatic islets by collating data from diverse sources.

bioRxiv 1d ago