RAD51AP1
No mentions found
This entity hasn't been tracked yet, or Iris is still building its knowledge base.
Related Articles from SNS
G quadruplex DNA facilitates a pervasive path to homologous recombination
Homologous recombination (HR) requires efficient homology search and strand invasion, yet how homologous templates are identified within the nucleus remains unclear. Here, we identify G-quadruplex (G4) DNA structures as pervasive effectors of template strand invasion and uncover the G4 helicase DHX36 as a potent suppressor of this process. DHX36 loss stabilizes G4s, enhances HR, and accelerates repair of replication-associated DNA breaks.