RGC
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Related Articles from SNS
The P2X7 receptor is an intermediate in the retinoic acid-signaling pathway that induces neuronal remodeling in retinitis pigmentosa
Photoreceptor degeneration drives electrophysiological remodeling in downstream retinal neurons, including hyperactive firing of retinal ganglion cells (RGCs) that degrades residual vision. Although Retinoic Acid (RA) and its receptor (RAR) are known to upregulate ion channel genes associated with RGC hyperactivity, these genes lack canonical RAR binding sites required for direct transcriptional regulation. Here, we identify P2X7 receptor (P2X7R) as a key intermediary in RA-induced...
FS-DVS: A Frequency-Selective Dynamic Visual Sensing Paradigm for Enhancing Information Completeness
arXiv:2606.06856v1 Announce Type: new Abstract: Dynamic vision sensors (DVS) offer exceptional temporal resolution and dynamic range by asynchronously reporting pixel-level intensity changes. However, conventional DVS rely on a per-pixel independent triggering mechanism, ignoring the spatial integration performed by biological retinal ganglion cells (RGCs). Consequently, they lack the contrast sensitivity function (CSF) and its inherent sensitivity to mid-spatial frequencies, which...
Stresses and fluid flow in lamina cribrosa through anisotropic poroelasticty
arXiv:2511.04726v2 Announce Type: replace Abstract: To investigate the mechanical correlations between intraocular pressure (IOP) variations and glaucoma, this study presents a linear transversely isotropic poroelastic model of the lamina cribrosa (LC) based on Reissner-Mindlin plate theory. A key feature of the proposed framework is its analytical tractability, which allows the governing poroelastic equations to be solved in closed form under appropriate mechanical and hydraulic boundary...