Ras
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Related Articles from SNS
Radiosensitization of Glioblastoma by the K-ras Inhibitor RMC-6236
Purpose: Glioblastoma (GBM) is characterized by poor clinical outcomes and marked resistance to radiotherapy. Because effective radiosensitizing strategies for GBM remain limited, we investigated whether inhibition of KRAS/RAS signaling could enhance radiation response in GBM. In particular, we evaluated the radiosensitizing potential of RMC-6236, an RAS(ON) multiselective inhibitor that suppresses active RAS signaling across multiple RAS-dependent states.
J-RAS: Mutual Adaptation for Medical Image Segmentation via Contrastive Retrieval-Augmented Joint Optimization
Announce Type: replace Abstract: Manual medical image segmentation by clinicians, though accurate, is time-consuming and variable across experts, whereas AI-based models automate this process but often underperform with limited data and domain shifts. Inspired by how pathology trainees acquire disease recognition skills through guided comparison with expert-annotated slides and histopathology atlas reference images, we propose Joint Retrieval-Augmented Segmentation (J-RAS). This framework...
Learned Response-Field Inertia Operator for HEC-RAS 2D Water-Surface Elevation Prediction
arXiv:2606.06385v1 Announce Type: new Abstract: This article presents a cross-dataset evaluation of learned native-cell surrogate models for solver-consistent water-surface elevation (WSE) prediction in HEC-RAS 2D. To avoid raster remapping error and information-access confounding, surrogates are evaluated directly on the original nonuniform computational cells under an explicit policy that separates static project inputs, current hydraulic state, project-input forcing, calibration-derived...
RAS: a Reliability Oriented Metric for Automatic Speech Recognition
arXiv:2604.24278v4 Announce Type: replace Abstract: Automatic speech recognition systems often produce confident yet incorrect transcriptions under noisy or ambiguous conditions, which can be misleading for both users and downstream applications. Standard evaluation based on Word Error Rate focuses solely on accuracy and fails to capture transcription reliability. We introduce an abstention-aware transcription framework that enables ASR models to explicitly abstain from uncertain segments.
RAS: a Reliability Oriented Metric for Automatic Speech Recognition
arXiv:2604.24278v3 Announce Type: replace Abstract: Automatic speech recognition systems often produce confident yet incorrect transcriptions under noisy or ambiguous conditions, which can be misleading for both users and downstream applications. Standard evaluation based on Word Error Rate focuses solely on accuracy and fails to capture transcription reliability. We introduce an abstention-aware transcription framework that enables ASR models to explicitly abstain from uncertain segments.
The WormFood CURE: Screening for bioactive metabolites that antagonize the Caenorhabditis elegans Ras signaling pathway
Course-based Undergraduate Research Experiences (CUREs) provide an accessible, scalable platform for scientific discovery. Here, we present the WormFood CURE, which mines environmental bacterial isolates for bioactive secondary metabolites using Caenorhabditis elegans phenotype suppression as a functional readout. Utilizing the multivulva (Muv) phenotype, our pilot cohort interrogated 41 wild bacterial isolates for suppression of Ras/MAPK signaling.
Robust spectral preconditioning for high-P\'{e}clet number convection-diffusion
arXiv:2509.17531v2 Announce Type: replace Abstract: We introduce a two-level hybrid restricted additive Schwarz (RAS) preconditioner for heterogeneous steady-state convection-diffusion equations at high P\'{e}clet numbers. Our construction builds on the multiscale spectral generalized finite element method (MS-GFEM), wherein the coarse space is spanned by locally optimal basis functions obtained from local generalized eigenproblems on operator-harmonic spaces. Extending the theory of Ma...
Newark mayor imposes curfew at Delaney Hall immigration detention centre
Newark mayor imposes curfew at Delaney Hall immigration detention centre New Jersey Governor Mikie Sherrill has called for the establishment of protected protest zones to minimise clashes with law enforcement. Ras Baraka, the mayor of Newark in New Jersey, has imposed a curfew on the area surrounding Delaney Hall, the immigration detention centre that has become a flashpoint in the debate over United States President Donald Trump’s mass deportation drive. The Sunday morning announcement came...
US: Newark mayor orders curfew after Delaney Hall protests
US: Newark mayor orders curfew after Delaney Hall protests June 1, 2026The mayor of the US city of Newark ordered a curfew around the Delaney Hall immigration detention center in the state of New Jersey due to ongoing demonstrations. The curfew will be in effect between 9:00 PM local time and 6:00 AM the following morning, Mayor Ras Baraka said in a statement, adding that the measure will remain in place until further notice. Pro-immigration protesters have been clashing with the police at...