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Agent libOS: A Library-OS-Inspired Runtime for Long-Running, Capability-Controlled LLM Agents
arXiv:2606.03895v1 Announce Type: new Abstract: Large language model (LLM) agents are evolving from request-response assistants into long-running software actors: they maintain state across model calls, fork subtasks, wait for external events, request human authority, generate tools, and perform side effects that must be resumed and audited. This paper presents Agent libOS, a library-OS-inspired runtime substrate for LLM agents. Agent libOS runs above a conventional host operating system; it...
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Quantifying Rodda and Graham Gait Classification from 3D Markerless Kinematics derived from a Single-view Video in a Heterogeneous Pediatric Clinical Cohort
arXiv:2605.11314v3 Announce Type: replace Abstract: Cerebral Palsy (CP) is a neurological disorder of movement and the most common cause of lifelong physical disability in childhood. Approximately 75% of children with CP are ambulatory, and accurate gait assessment is central to preserving walking function, which deteriorates by mid-adulthood in a quarter to half of adults with CP. The Rodda and Graham classification system quantifies sagittal-plane gait deviations using ankle and knee...
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone
Abstract Whale falls are biodiversity oases at seabeds1,2,3,4,5,6, yet their record from the oceans has remained sparse and fragmentary6,7. Here we report the discovery of a vast whale necropolis in the Diamantina Zone (4,616- to 7,001-m depth), extending about 1,200 km along the sea floor of the southeastern Indian Ocean. This area has a deep and extensive accumulation comprising five modern natural whale-fall communities and 476 fossil cetaceans recorded.
Cooperation, privatization and cheating in microbial exoenzyme synthesis: theoretical analysis in view of biotechnological applications
This study presents a mathematical framework for investigating the dynamics of coexistence and competition among heterotrophic microbes across different time scales. Focusing on metabolic interactions, we examine how three strategies: public metabolizing, private metabolizing, and cheating, shape population behaviour. The framework integrates generalized Lotka-Volterra dynamics with evolutionary game theory to capture the effects of resource exchange, particularly glucose made available by...
VoidZero Is Joining Cloudflare
VoidZero, the company behind Vite, Vitest, Rolldown, Oxc, and Vite+, is joining Cloudflare. As part of this change, all team members of VoidZero are joining Cloudflare, too. Before saying anything else, we want to make the most important thing clear: Vite, Vitest, Rolldown, Oxc, and Vite+ will stay open source, vendor-agnostic, and community-driven.
Crystal Nights by Greg Egan
Publication history - Interzone #215, April 2008. - Free podcast at Transmissions From Beyond. [Site no longer active] - Oceanic (collection, Orion) -
Bacteria uncover distinct strategy to import rare sugar polymers, crystal structures show
Bacteria uncover distinct strategy to import rare sugar polymers, crystal structures show Sadie Harley Scientific Editor Andrew Zinin Lead Editor Even though sugars are often framed as simple sources of energy, they also serve as structurally complex and functionally diverse molecules that mediate interactions between organisms. Among these, β-1,2-glucans, which are a class of glucose-based polymers, stand out for their varied and sometimes subtle roles. Found across a wide range of...