Rev Foster
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Alan Bates brands Post Office compensation scheme an 'utter disaster'
Alan Bates brands Post Office compensation scheme an 'utter disaster' Post Office scandal campaigner Alan Bates slams slow progress of compensation to victims of the Horizon scandal as he calls for others to be taken out of control of the government Hero Alan Bates has branded the compensation schemes set-up for fellow victims of the Post Office Horizon IT scandal “an utter disaster”. Postmaster Sir Alan, who fought to expose the injustice for others, told MPs: “There are so many reasons why...
Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).
A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone
Abstract Whale falls are biodiversity oases at seabeds1,2,3,4,5,6, yet their record from the oceans has remained sparse and fragmentary6,7. Here we report the discovery of a vast whale necropolis in the Diamantina Zone (4,616- to 7,001-m depth), extending about 1,200 km along the sea floor of the southeastern Indian Ocean. This area has a deep and extensive accumulation comprising five modern natural whale-fall communities and 476 fossil cetaceans recorded.
Building user-driven climate adaptation products
Abstract Climate adaptation products have traditionally been developed using a supply-driven model reliant on available climate information, leading to usability gaps1,2,3,4. To better meet user needs, the climate services field has recognized a need to shift towards a demand-driven model emphasizing co-production, that is, user-driven, scientifically informed products created through shared knowledge practices1,2,3,4,5. However, co-production can be challenging, especially for researchers...