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Osteopontin Upregulation Defines a Pre-Rupture State in Thoracic Aortic Aneurysms in Mice and Humans

Background: Thoracic aortic aneurysm (TAA) is a life-threatening condition with an unpredictable lisk of rupture. Current clinical parameters have limited ability to accurately predict imminent rupture. Osteopontin (OPN) has been implicated in aortic aneurysm pathology, however, it role as a marker of imminent rupture remains.

bioRxiv 10d ago

Hemodynamic Overlap Between Ruptured and Unruptured Cerebral Aneurysms Using an In-House Parallel C++ Finite Element Solver

arXiv:2606.00072v1 Announce Type: new Abstract: Cerebral aneurysm rupture has long been associated with abnormal hemodynamic conditions, particularly wall shear stress (WSS)-related flow behavior. Although aneurysm rupture is widely recognized as a multifactorial phenomenon involving complex interactions between geometry, flow structures, and multiple hemodynamic quantities, WSS-based parameters remain among the most commonly reported metrics in computational aneurysm studies. In the present...

arXiv Physics 8d ago

Effect of Spatially Heterogeneous Mucin Coverage on Tear Film Stability and Ruptur

arXiv:2606.07192v1 Announce Type: new Abstract: Clinical observations of dry eyes reveal that tear film breakup is associated with spatial variations in corneal wettability arising from non-uniform mucin coverage. Motivated by these observations, we develop a thin-film model to investigate the influence of heterogeneous wettability on tear film stability. Heterogeneity in mucin coverage is incorporated through variations in the Hamaker constant and slip length along the corneal surface.

arXiv Physics 2d ago

Fizzy drink cans recalled as they 'may rupture unexpectedly'

Dalston's Pineapple Soda as asking people to throw away affected cans of its pineapple drink over fears they could cause injury.

BBC UK 4d ago

Fizzy drink cans recalled as they 'may rupture unexpectedly'

Dalston's Pineapple Soda as asking people to throw away affected cans of its pineapple drink over fears they could cause injury.

BBC News 4d ago

Fizzy drink cans recalled as they 'may rupture unexpectedly'

Dalston's Pineapple Soda as asking people to throw away affected cans of its pineapple drink over fears they could cause injury.

BBC Business 4d ago

Fizzy drink cans recalled as they 'may rupture unexpectedly'

Dalston's Pineapple Soda as asking people to throw away affected cans of its pineapple drink over fears they could cause injury.

BBC News 4d ago

Fizzy drink cans recalled as they 'may rupture unexpectedly'

Dalston's Pineapple Soda as asking people to throw away affected cans of its pineapple drink over fears they could cause injury.

BBC Business 4d ago

Washington state crews find body of another victim in paper mill explosion

Discovery brings death toll from chemical tank rupture in Longview to nine, with two workers still unaccounted forCrews on Friday recovered the remains of one more victim of a massive chemical tank rupture at a paper mill in Washington state, bringing the death toll to nine people and leaving two workers still unaccounted for. Among the 11 workers presumed killed in the disaster were two brothers who worked there together, a trivia champ and an electrician who would help his farmer neighbors...

The Guardian UK 11d ago