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Related Articles from SNS
MTAP deficiency is a novel biomarker in neuroendocrine neoplasms of the lung
Abstract Introduction: MTAP emerges as potential predictive biomarker for MTA-cooperative PRMT5 inhibitors. Although MTAP attracts increasing attention in non-small cell lung cancer, its role in pulmonary neuroendocrine neoplasms (NENs) remains largely unexplored. Methods: Here, we assessed the prevalence of MTAP deficiency in 209 pulmonary NENs using immunohistochemistry (IHC).