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Improved Approximation Algorithms and Hardness Results for Shortest Common Superstring with Reverse Complements

Announce Type: replace Abstract: The Shortest Common Superstring (SCS) problem is a fundamental task in sequence analysis. In genome assembly, however, the double-stranded nature of DNA implies that each fragment may occur either in its original orientation or as its reverse complement. This motivates the Shortest Common Superstring with Reverse Complements (SCS-RC) problem, which asks for a shortest string that contains, for each input string, either the string itself or its reverse...

arXiv CS 9d ago