Schizophrenia
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Patient-Derived Air-Liquid Interface Forebrain Organoids Reveal Functional Synaptic Deficits in Schizophrenia
Schizophrenia (SCZ) is a severe and debilitating neurodevelopmental disorder with lifelong impact on everyday life. Disruptions in synapse functions play a key role in its complex and poorly understood etiological and pathological mechanisms. Here, we investigated both the molecular composition and the spontaneous and stimulated functional properties of synapses in neural organoids from SCZ individuals.
A French hospital enlists donkeys in mental health care — and patients approve
From depression to schizophrenia, France's only hospital-based animal therapy unit is making the case that four legs can go where medicine alone cannot. When life gets you down, try petting a donkey — at least, that is one of the prescriptions at the Ville-Evrard hospital complex east of Paris. Tucked within its grounds, among 19th-century farm buildings and woodland, five donkeys are doing some of the mental health heavy lifting between hay-munching breaks.
A Sydney mother asked police to lock her up. 11 days later, she was dead
The last holding place Sat 6 Jun 2026 at 4:59am Tammy Shipley walked into a police station and asked to be arrested. She just wanted to be safe. Within days she was under 24-hour surveillance.
The circus freaks of open source
The masterwork of Terry A. Davis is his eclectic operating system, TempleOS, which he worked on until his tragic death in 2018. In terms of technical excellence, TempleOS rates well in some respects and poorly in others. For example, it earns the achievement, coveted in OS dev circles, of being self-hosted.1 TempleOS is written in Terry’s own bespoke dialect of C and includes an editor, interpreter, and compiler, as well as a number of original games.
Police beat a woman in a Sydney street. Their own camera captured their cruelty
Jodi Knott suffered 'gratuitous cruelty' at the hands of police. Her family wants the public to see what they did Sun 31 May 2026 at 5:06am The shaky video on the laptop shows a naked woman crouching under a tree by a Western Sydney street, experiencing a psychotic episode. Plain-clothes NSW police officer Senior Constable Nathan Black puts on blue surgical gloves.
Are some people wired to see ghosts? A psychologist explains what makes paranormal experiences more likely
Are some people wired to see ghosts? A psychologist explains what makes paranormal experiences more likely Is my brain wired to never see a ghost? A psychologist on three factors that make a paranormal experience more likely Around 1 in 5 Americans say they've seen a ghost.
Scientists reverse anxiety by fixing a tiny brain circuit
Scientists reverse anxiety by fixing a tiny brain circuit - Date: - June 3, 2026 - Source: - Universidad Miguel Hernandez de Elche - Summary: - A newly identified group of amygdala neurons appears to play a central role in anxiety and social behavior. Restoring normal activity in this tiny brain circuit reversed anxiety and social deficits in mice, revealing a promising new target for future treatments. - Share: Scientists have identified a specific brain circuit that appears to play a major...
I was recently diagnosed with anti-NMDA receptor encephalitis
I was recently diagnosed with anti-NMDA receptor encephalitis. It is an autoimmune disorder where your body’s normally helpful antibodies start acting strangely. This leads to inflammation in the brain.
Chilling moment daughter 'calmly' tells police 'I killed my mum' after 'strangling' her on Christmas Day
Chilling moment daughter 'calmly' tells police 'I killed my mum' after 'strangling' her on Christmas Day Stefania Glowka, 64, is on trial for the murder of Tamara Glowka, 86, at their Wiltshire home, she has denied murder but pleaded guilty to manslaughter following her mother's Christmas Day death This is the disturbing moment a woman "calmly" told police that she had killed her own mother after failing to take her own life on Christmas Day. Stefania Glowka, 64, has gone on trial accused of...
People taking common sleep drug may not realize they're too impaired to drive, study finds
A popular antipsychotic medication was found to reduce obstructive sleep apnea (OSA) – but it also led to impaired driving the next morning. That’s according to a small randomized controlled trial published in the Annals of the American Thoracic Society. Researchers from Flinders University in Adelaide, Australia, conducted the study in 15 adults with OSA who also had difficulty maintaining sleep.