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Posture and support geometry, rather than body size, dictate lateral dynamic stability in walking mammalian quadrupeds

Body size and limb posture vary widely across mammals and are expected to shape locomotor stability, yet direct comparative evidence remains limited. Here, we tested whether smaller, crouched mammals exhibit greater lateral dynamic stability than larger, more upright species by comparing treadmill walking in mice and cats at dynamically similar speeds. Using kinematic analyses and size normalized measures of stability, we show that mice are substantially more laterally stable than cats.

bioRxiv 1d ago

Robust Multi-Mutant Protein Stability Prediction from a Fine-Tuned Evolutionary Scale Model

Recently, high-throughput experimental techniques have propelled improvements in deep learning-based prediction of mutation effects on protein stability. However, leading stability predictors still struggle to predict the combined effect of multiple mutations and prefer mutations that negatively impact other properties, including expressibility. To mitigate these limitations, we apply Low-Rank Adaptation (LoRA) to specialize ESM3 for stability prediction by fine-tuning on the Megascale...

bioRxiv 5d ago

China unveils first-of-its-kind 'dual-core' quantum computer — its makers say it improves stability and efficiency

China unveils first-of-its-kind 'dual-core' quantum computer — its makers say it improves stability and efficiency A new Chinese quantum computing system pairs two independent neutral-atom arrays in one processor, aiming to boost stability, efficiency and scalability. A Chinese company has unveiled what its researchers are calling the world’s first "dual-core" quantum computer. It's a neutral-atom system designed to improve stability, efficiency and error correction by pairing two...

Live Science 1d ago

Developing engineering strategies to enhance the genetic stability of fatty alcohol-producing strains for production scale-up

Robust strain stability is essential for industrial-scale fatty alcohol production, as metabolic burden and toxicity not only constrain productivity but also create selective pressure for low-producing or non-producing subpopulations. This genetic instability leads to genetic heterogeneity and compromises strain performance during large-scale fermentation. In this study, we investigated the production stability of fatty alcohol-producing Yarrowia lipolytica strains and developed systematic...

bioRxiv 7d ago

Long-term laser frequency stabilization with an FPGA-controlled scanning cavity

arXiv:2606.09720v1 Announce Type: new Abstract: We present an FPGA-based implementation of a scanning transfer cavity lock (STCL) for laser frequency stabilization, allowing for the simultaneous stabilization of multiple laser sources with respect to a single reference laser by means of a continuously scanned Fabry-Perot cavity. By exploiting the FPGA architecture to simultaneously perform cavity scanning, peak detection, and feedback actuation, we minimize latency and allow independent...

arXiv Physics 1d ago

Uniform Stability and Generalization Error of GD and SGD on Fixed-Point Parameters

Announce Type: new Abstract: We analyze generalization error, uniform stability, and uniform argument stability of gradient descent (GD) and stochastic gradient descent (SGD) over discrete parameter spaces, where each update involves deterministic or stochastic rounding. We show that deterministic rounding degrades the generalization error of GD on convex, Lipschitz, and smooth loss functions, increasing the rate from $O(T/n)$ to $O(T/\sqrt{n})$, and establish matching lower bounds. We...

arXiv CS 2d ago

Stabilization-free virtual element methods based on finite element interpolation

Announce Type: new Abstract: In this paper, we introduce a new framework for designing stabilization-free virtual element methods (VEMs) based on an finite element interpolation-based strategy, where we can simultaneously eliminate the stabilization terms in the discretizations of diffusion and reaction terms. The core idea is to construct a computable, polynomial-preserving, and norm-equivalent interpolation operator from the virtual element space to a (local) finite element space....

arXiv CS 8d ago

Exploring and Exploiting Stability in Latent Flow Matching

Announce Type: replace Abstract: In this work, we show that Latent Flow-Matching (LFM) models are robust to different types of perturbations, including data reduction and model capacity shrinkage. We characterize this stability by these models' tendency to generate similar outputs under identical noise seeds. We provide a perspective relating this phenomenon to flow matching theory, which indicates that this stability is inherent to the FM objective.

arXiv CS 8d ago

Stability beyond Bounded Differences: Sharp Generalization Bounds under Finite $L_p$ Moments

arXiv:2606.06855v1 Announce Type: cross Abstract: While algorithmic stability is a central tool for understanding generalization of learning algorithms, existing high-probability guarantees typically rely on uniform boundedness or sub-Gaussian/sub-Weibull tail assumptions, which can be overly restrictive for modern settings with heavy-tailed or unbounded losses. We develop a stability-based framework that requires only a finite $L_p$ moment condition. Our first contribution is sharp...

arXiv CS 2d ago

Impact of a Soft Wearable Back-Support Device on Postural Stability during Trip-Like Perturbations

arXiv:2606.02888v1 Announce Type: new Abstract: The effectiveness of a soft wearable back-support device in enhancing postural stability was investigated under trip-like perturbations using two experimental paradigms: perturbed standing and perturbed walking. Healthy subjects completed trials under three different back-support conditions: no device, device worn with low stiffness, and device activated with high stiffness. Whole-body stability was quantified using the minimum Margin of...

arXiv CS 7d ago