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TPR3

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CONSERVATION AND DIVERGENCE WITHIN THE ARABIDOPSIS TPL/TPR COREPRESSOR FAMILY

The TOPLESS (TPL) and TOPLESS-RELATED (TPR1-TPR4) corepressors, collectively the Arabidopsis TPX family, are recruited by client proteins to regulate nearly every major plant regulatory program. Here, we dissect the conservation and divergence between paralogs using a combination of higher-order genetics, transcriptomics, and a synthetic repression assay. TPL, TPR1, and TPR4 were found to act as the primary repressors for many pathways, while TPR2 and TPR3 played a lesser or sometimes...

bioRxiv 4d ago