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Warning issued to anyone taking hormone or testosterone replacement therapy

Warning issued to anyone taking hormone or testosterone replacement therapy People have been warned of the risks of accidental exposure and what signs to look out for The Veterinary Medicines Directorate (VMD) has today, June 11, issued a warning to anyone taking hormone replacement therapy (HRT) and testosterone replacement therapy (TRT). The alert is primarily aimed at people who regularly come into contact with animals and pets, including cats and dogs. Pets are naturally curious,...

Daily Mirror 3h ago

Organoid-T cell co-cultures functionally stratify tumor-reactive T cells and their responses to immune checkpoint inhibitors

Tumor-reactive T cells (TRTs) are critical for anti-tumor immunity but are incompletely captured by current assays, which fail to reproduce tumor-specific antigen diversity. Here, we show that multiplex functional profiling of patient-derived tumor organoid-T cell co-cultures (PDOTs) enables robust identification of TRTs across CD8, CD4, and double-negative (DN) T cell populations. Single activation markers underestimated TRT responses, whereas integrated analysis revealed broader functional...

bioRxiv 11d ago

Baby among 8 people killed after bus crashes and catches fire in Turkey

Baby among 8 people killed after bus crashes and catches fire in Turkey Eight people, including a nine-month-old baby, have been killed after a bus crashed and caught fire in western Turkey - this is a breaking story A bus crashed and caught fire in western Turkey, leaving eight people dead - including a 9-month-old baby boy - local media report. The bus, owned by Pamukkale Tourism, crashed into highway barriers in Denizli province at 1.40am TRT on Sunday (1.40pm BST on Saturday) while...

Daily Mirror 10d ago

How Turkey Hacked the Hair Transplant Industry

The astounding growth of the hair-transplant industry in Turkey is not just a medical tourism success story; it’s also a tale of “hacked” medical equipment and algorithmic craftsmanship. From a biological and evolutionary perspective, human hair is often viewed as an unremarkable mass of keratin that still plays some important functions—protecting our scalps from the sun’s harmful ultraviolet rays and regulating our body temperatures—but, for the most part, is no longer essential to our...

Wired 11d ago

26-year-old woman with 60-year-old husband says people think he's her dad

26-year-old woman with 60-year-old husband says people think he's her dad The couple say 'people are entitled to their opinions' When Gracen Geagan walks into a coffee shop with her husband she is regularly asked what her dad wants to order. This comes as no surprise as Gracen is 26 and her husband Kevin is 60.

Daily Mirror 9d ago

When Both Parties Try to Out-Macho Each Other

Subscribe here: Apple Podcasts | Spotify | YouTube | Overcast | Pocket CastsA couple of weeks ago, Democrats posted a photo of James Talarico, the U.S. Senate candidate in Texas, captioned “November, here we come.” Talarico, strangely alone at a picnic table, is wearing a lone-star flag button-down, and he has four baskets piled with fried foods in front of him and, most significant, a turkey leg thicker than his forearm jammed in his mouth. Presumably, this image is a response to...

The Atlantic 2h ago