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Related Articles from SNS
Annotation-Informed Block-Sparse Bayesian Modeling for cis-Expression Prediction
arXiv:2606.00483v1 Announce Type: cross Abstract: Genotype-based cis-expression prediction depends on accurately modeling local regulatory architecture. We present block-sparse Bayesian sparse linear mixed model (bsBSLMM), an extension of Bayesian sparse linear mixed model (BSLMM) that incorporates linkage disequilibrium (LD)-block spike-and-slab sparsity and a transcription start site (TSS)-informed SNP inclusion prior. Across 23,098 genes from GEUVADIS European-ancestry lymphoblastoid cell...
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Hundreds of ships cross the Strait of Hormuz, some are going 'dark' to do it
US and Iran negotiations in 'deadlock', but ships are finding ways to cross the Strait of Hormuz Tue 9 Jun 2026 at 4:56am Marine traffic observers have revealed hundreds of commercial ships have crossed out of the Strait of Hormuz, often by taking "dark" journeys through Iran's "tollbooth route" or with the guidance of the United States. Analysts also say some Iranian tankers are likely slipping past the US blockade in the opposite direction and entering Iranian waters to be used to store...