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Reachability-Preserving Minimum Edge Cut Problem and Applications in Biology
Biological pathway analysis often requires identifying interventions that block reachability to an undesirable state, such as a disease-associated module, toxic byproduct, or adverse phenotype, while preserving reachability among essential biological functions. Motivated by this setting, we study the Reachability Preserving Minimum Edge Cut (RPMEC) problem: given protected terminals (s_1) and (s_2) and a target terminal (t), the goal is to remove a minimum-cost set of edges that separates...
Major travel disruption to and from Heathrow airport after burst pipe halts trains
Major travel disruption to and from Heathrow airport after burst pipe halts trains A signal failure caused by flooding at Heathrow Terminals 2 and 3 means there are no train services to Heathrow today - Bookmark - CommentsGo to comments Passengers are facing major travel disruption travelling to and from Heathrow airport after a burst pipe halted train services. Transport for London said there were no services on the Elizabeth Line between Hayes and Harlington and Heathrow due to a signal...
Sudden storm: 3 Air India aircraft damaged at IGIA by ground equipments
The sudden rainstorm that hit IGI Airport’s Terminal 2 (T2) on Sunday evening left three aircraft damaged when they were hit by ground support equipment which moved from their positions in strong winds. Of the three Air India single aisle aircraft, one will now be grounded for a few days for repairs while the other two could start flying this week. “There was no weather warning given for a storm.
First Oil Supertanker Moors at Kharg Island in Almost a Month
An image from the European Union's Sentinel 1 satellite shows a very large crude carrier moored at Iran's Kharg Island oil terminal on June 2, 2026, the first in nearly a month.
Cloning a Sennheiser BA2015 battery pack
One of the annoying things about electronics is that so many companies must make their own incompatible battery packs. For many products these are expensive but at some level still reasonable, the battery pack contains the protection circuitry and some guaranteed high quality Li-ion cells. This is not one of those devices.
NEK kinase TcRDK2 controls differentiation, host-cell infection, and remodeling of the translation initiation machinery in Trypanosoma cruzi
Trypanosoma cruzi, the etiologic agent of Chagas disease, alternates between replicative epimastigotes and amastigotes and non-dividing, mammal-infective metacyclic and bloodstream trypomastigotes. Protein phosphorylation is a major regulatory mechanism in trypanosomatids, whose kinomes reveal an expanded family of NIMA-related kinases (NEKs). Here, we investigated the role of T. cruzi RDK2 (Repressor of Differentiation Kinase 2), a conserved NEK that carries a C-terminal pleckstrin homology...
Chipotlai Max
The AI coding agent that steals Chipotle's support bot. Free inference paid for by burritos. "Every line of code now comes with chips & salsa."
The intracies of modern camera lens repair (2024)
Sigma 45mm f/2.8 Lens Repair & Analysis [05.12.24] I have a camera gear collection problem and as part of my personal 12 step plan, I restrict myself from purchasing functioning lenses. This sounds illogical, and it frankly is, but it's very hard for me to resist heavily discounted lenses.
No trains running to and from Heathrow Airport
No trains running to and from Heathrow Airport There are no trains going in and out of Heathrow after a burst water main caused flooding at an airport train station. Passengers are asked to allow extra time and arrange alternative means of travel. Heathrow Express, which normally runs from Paddington to the airport every 15 minutes, is closed in both directions due to a fault with the signalling system, according to the service's website.
Heathrow trains live: Elizabeth Line suspended as no services running to airport
Heathrow trains live: Elizabeth Line suspended as no services running to airport The Elizabeth Line and Heathrow Express are suspended while the Piccadilly Line is also closed There are no trains going in and out of Heathrow Airport after flooding and a major signal fault. Passengers are asked to allow extra time and replacement bus services have been laid on. Heathrow Express, which normally runs from Paddington to the airport every 15 minutes, is closed in both directions due to a fault...