VTA
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Related Articles from SNS
Cell-type targeted CRISPR/Cas9 Clock knockdown in mouse VTA dopamine neurons alter sleep, behavior, and cellular excitability
Bipolar disorder (BD) is a severe psychiatric disease characterized by recurrent mania, depression, and circadian rhythm disruption. Among circadian regulators implicated in mood-related dysfunction, Clock has emerged as a particularly strong mechanistic candidate. However, cell type-specific functions of Clock within mood-relevant circuits remain incompletely defined.
Multiplexed dopamine neurons predominate in the ventral midbrain of young macaques
Dopamine (DA) is important in many fundamental behaviors, including positive and negative reinforcement, incentive salience, and decision-making. This behavioral diversity is now known to be due, in part, to neurotransmitter diversity, based on rodent models. To address DA neuron transmitter properties in higher species, we examined the ventral midbrain in 5 young macaques (3 male, 2 females, 3-6 years) using RNAscope in situ hybridization for tyrosine hydroxylase (TH), vesicular glutamate...
San Francisco Bay Area: A travel guide to the 2026 World Cup host
Levi’s Stadium in Santa Clara will host six fixtures during the World Cup – five group-stage games and a Round of 32 clash. The San Francisco Bay Area loves its big sporting events. With the NBA All-Star Game, NFL Super Bowl and now the FIFA World Cup all in a 16-month span, Northern California has been a non-stop host.