Vascular Institute
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Diabetes drug could slash risk of fatal heart condition in one group, scientists reveal
A diabetes drug could help lower the risk of heart failure in certain patients. A new study published in Nature Medicine analyzed how SGLT2 inhibitor dapagliflozin, a medication used to treat type 2 diabetes, could help prevent heart failure in people with rare genetic variants linked to cardiomyopathy (a progressive disease of the heart muscle).Using data from the DECLARE-TIMI 58 trial, researchers from Harvard Medical School, Mass General Brigham and MIT looked at more than 12,000 adults...
Doctor reveals 4 health markers that may predict heart attack and stroke risk
For decades, LDL cholesterol has been one of the most talked-about numbers in heart health. Often called the "bad cholesterol," elevated LDL levels have been linked to the buildup of fatty plaques inside arteries, a process known as atherosclerosis. Over time, these plaques can narrow or block blood vessels supplying the heart and brain, increasing the risk of heart attacks and strokes.
Predicting the risk of colorectal anastomotic leak based on preoperative mapping of the blood supply of the bowel
arXiv:2606.02156v1 Announce Type: cross Abstract: Anastomotic leak remains one of the most serious complications following colorectal cancer surgery, substantially affecting patient outcomes, recovery trajectories, and healthcare costs. Despite advances in imaging technology, current preoperative assessment relies only on clinical assessment, a process that is subjective, error-prone, and highly dependent on individual expertise.
Magnesium transporter discovery could improve rice nutrition and taste
Magnesium transporter discovery could improve rice nutrition and taste Sadie Harley Scientific Editor Robert Egan Associate Editor Rice is a staple food for nearly half the global population and an important dietary source of magnesium, a mineral essential for human health, plant growth and energy metabolism. Although magnesium is known to influence grain quality and taste, the biological mechanism controlling how the mineral reaches rice grains has remained largely unknown. Understanding...
Comparison of Automated White Matter Lesion Segmentation Approaches for Use in Large, Multi-Site Data Analyses in Parkinson's Disease
Background: Parkinson's disease (PD) is the second most common neurodegenerative disorder. PD currently lacks effective disease-modifying treatments, likely due to its diverse clinical features and underlying neuropathology. The vascular role in PD is emerging, with vascular mechanisms increasingly implicated, yet the literature remains conflicted, motivating large-data analyses with greater statistical power.