Xue Chaoyou

RNA-guided transposon mechanics show use of figure-eight intermediate and direct-transfer route

RNA-guided transposon mechanics show use of figure-eight intermediate and direct-transfer route Gaby Clark Scientific Editor Robert Egan Associate Editor IS110 transposons are a large, diverse family of bacterial insertion sequences (IS elements)—small, mobile DNA elements that can move from one genomic location to another. They have recently attracted broad interest due to the finding that some of these transposons use a bridge RNA (bRNA) to recognize both donor DNA and target DNA. Upon...