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A-to-I mRNA editing recodes CqsA and affects T6SS-mediated killing in Vibrio

Adenosine-to-inosine (A-to-I) RNA editing alters genetic information post-transcriptionally, yet its ecological and evolutionary significance in bacteria remains largely unexplored. Here, we show that endogenous RNA editing has functional consequences in bacteria. Using Vibrio alginolyticus as a model, we identified 38 editing events - the highest number reported for any bacterium to date.

bioRxiv 2d ago