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Generative Drifting is Secretly Score Matching: a Spectral and Variational Perspective
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SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
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VaN3Twin: the Multi-Technology V2X Digital Twin with Ray-Tracing in the Loop
arXiv:2505.14184v3 Announce Type: replace Abstract: This paper presents VaN3Twin-the first open-source, full-stack Network Digital Twin (NDT) framework for simulating the coexistence of multiple Vehicle-to-Everything (V2X) communication technologies with accurate physical-layer modeling via ray tracing. VaN3Twin extends the ms-van3t simulator by integrating Sionna Ray Tracer (RT) in the loop, enabling high-fidelity representation of wireless propagation, including diverse Line-of-Sight (LoS)...
Safer radiotherapy: triannual event analysis and learning
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Lignin to adipic acid in a high-yield chemical and biological redox process
Abstract Viable manufacturing pathways to produce bio-based chemicals from renewable feedstocks, such as lignin derived from plant biomass, are needed to decarbonize the chemicals manufacturing sector. Converting the recalcitrant lignin polymer to valuable bioproducts remains a longstanding challenge in biorefining, with the highest reported single-product yield from lignin currently around 20 wt% (refs. Most existing lignin depolymerization strategies target aryl–ether bond cleavage, which...
strace-ui, Bonsai_term, and the TUI renaissance
We’ve always found strace useful but somewhat hard to work with. Its output is often inscrutable, it’s hard to follow subprocesses or threads, and if you want to filter syscalls you have to rerun the trace with a flag for each one. What you want in debugging is a tool for exploring, refining, etc., but strace can make this difficult.