monoterpenoid
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Chemists unlock first total synthesis of rare plant alkaloid tied to anticancer activity
Plants are undeniably one of nature's most promising sources of new medicines, with monoterpenoid indole alkaloids (MIAs) being a great example. Some intricate compounds are built from multiple-linked chemical units that form highly complex three-dimensional structures. Because of their size and shape, scientists believe such oligomeric MIAs may be able to interfere with specific protein–protein interactions inside cells—a biological target that conventional small-molecule drugs often...
Amazon rainforest emits new stress-defense molecules during El Niño drought
Amazon rainforest emits new stress-defense molecules during El Niño drought Gaby Clark Scientific Editor Robert Egan Associate Editor The Amazon rainforest responded to the most severe drought ever recorded in the basin with an unexpected defense mechanism. Researchers at the Max Planck Institute for Chemistry in Mainz, Germany, found that during and after the intense 2023–2024 El Niño cycle, the most intense drought ever recorded in the region, vegetation significantly changed its chemical...