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First ever guidelines released to screen for condition that impacts 9 in 10 Americans
First ever guidelines released to screen for condition that impacts 9 in 10 Americans Doctors say earlier screening could help save lives - Bookmark - CommentsGo to comments Some 90 percent of Americans have at least one risk factor for cardiovascular-kidney-metabolic – or CKM – syndrome, a term for potentially life-threatening conditions that are all connected. Now, experts at the American Heart Association say more of the country should be screened for one particular risk factor in the...
Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
Sleep apnea’s hidden heart disease trigger found in the gut
Sleep apnea’s hidden heart disease trigger found in the gut - Date: - June 9, 2026 - Source: - American Society for Microbiology - Summary: - A surprising gut-heart connection may help explain why sleep apnea increases the risk of cardiovascular disease. In mice, disabling a bile acid receptor called FXR sharply reduced plaque buildup, opening the door to potential new treatments based on gut microbes and their chemical signals. - Share: Millions of people worldwide live with obstructive...
What to do if someone is having a stroke, after Jill Biden revealed debate-night fears
Former First Lady Jill Biden has expressed her concerns about former President Joe Biden’s health status, noting that she feared he was having a stroke during a 2024 debate. The then-president struggled his way through the performance, with long periods of silence, confused facial expressions and stammered speech. In a recent interview with CBS, Jill Biden commented that she was "frightened.""I
One weight loss change helps cuts cholesterol and blood pressure
One weight loss change helps cuts cholesterol and blood pressure The research says anything is better than nothing Regular exercise should be a "critical" component of any attempt to lose weight, according to a new report. Physical activity - whether it be jogging, swimming, walking or cycling - improves blood pressure, insulin sensitivity, cholesterol levels and general fitness in adults who are overweight or obesity, say scientists.
Wholesome Direct returns June 6 with a slew of joyful games
Wholesome Direct returns June 6 with a slew of joyful games The hype is steadily building around Summer Game Fest 2026 and the show's June calendar is starting to fill out. The fine folks at Wholesome Games will host their seventh annual digital showcase on Saturday, June 6 at 12PM ET on YouTube and Twitch, featuring more than 50 joyful and just plain adorable games from new and established studios alike.
Should you take nutrition advice from a chatbot? Experts urge caution
Should you take nutrition advice from a chatbot? Experts urge caution Readers share their experiences asking chatbots for help with meal planning. It went well… until it didn’t.
Dirty soda drinks are everywhere, but doctors warn of health risks: 'Metabolic disaster'
The latest beverage trend is far from clean – and it’s raising red flags with doctors. Known as a "dirty soda," it’s a soft drink that also includes a combination of added ingredients, such as flavored syrups, creamers, fruit juices and other garnishes. The result is a sweet beverage that’s a combination of a soda, mocktail and dessert.
Trump’s library team claims they can’t find a single Twitter DM despite president’s 25,000 tweets during his first term
Trump’s library team claims they can’t find a single Twitter DM despite president’s 25,000 tweets during his first term Court records show Twitter identified at least 32 Twitter DMs sent or received by the president before January 6 - Bookmark - CommentsGo to comments Donald Trump’s newly launched presidential library says it cannot find a single direct message sent by the president from his Twitter account despite the prolific poster firing off thousands of tweets during his first...