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Palantir Contracts Have Become ‘An Unacceptable Point of Weakness,’ UK Politicians Warn
A bipartisan group of UK politicians is sounding the alarm over the country's partnership with the data analytics company Palantir. In a report published Tuesday, the 11 members of Parliament’s Science, Innovation, and Technology Committee warned that the country’s ballooning reliance on Palantir’s technology “represents an unacceptable point of weakness” that could hand the company overwhelming bargaining power in future negotiations. “We know that with vendor lock-in, over time, we’ll get...
Measurement of reactor neutrino oscillation with the first JUNO data
Abstract Neutrino oscillations (see refs. 1,2 and references therein), a quantum effect manifesting at macroscopic scales, are governed by lepton flavour mixing angles and neutrino mass-squared differences3 that are fundamental parameters of particle physics, representing phenomena beyond the Standard Model. Precision measurements of these parameters are essential for testing the completeness of the three-flavour framework, determining the mass ordering of neutrinos and probing possible new...
Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).
Nature Index 2026 Research Leaders rankings: are China’s East Asian neighbours keeping pace with it?
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In situ nanocrystal confinement for efficient blue perovskite LEDs
Abstract Metal halide perovskites have emerged as promising semiconductors for light-emitting diodes (LEDs) owing to their excellent luminescence properties1. However, their performance remains limited, primarily owing to the inherent contradiction between ‘high crystallinity’ and ‘small size’ in the in situ synthesis of perovskite nanocrystals on substrates. Here we report efficient blue perovskite LEDs (PeLEDs) achieved via in situ polymerization-driven nanocrystal confinement to...
Rat, flies and rot: Havana’s trash crisis spirals out of control
Rat, flies and rot: Havana’s trash crisis spirals out of control For months, residents of Havana — home to 2 million of Cuba’s almost 10 million residents — have lived with piles of garbage accumulating on almost every street corner - Bookmark Havana’s streets are increasingly choked with mountains of rotting refuse, transforming the vibrant Cuban capital into a landscape of despair and disease. Residents across the city are grappling with an escalating garbage crisis, a stark consequence of...
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
UK banks offered access to OpenAI’s GPT-5.5 amid exclusion from Anthropic’s Glasswing expansion
UK banks are set to receive access to OpenAI’s GPT-5.5 Cyber after being excluded from Anthropic’s latest expansion of Project Glasswing. Project Glasswing, and access to the Mythos Preview model, is geared toward ensuring critical infrastructure providers are prepared to handle the threat posed by advanced AI models, once they inevitably make their way into the public domain, and therefore the hands of attackers. However, amid a fourfold expansion of Glasswing’s partners, only JPMorganChase...
UK, US and Australia to develop 'cutting-edge' underwater drone technology
The new technology is expected to be ready by 2027 and is designed to help defend critical subsea cables and pipelines. Defence ministers from the UK, Australia and the US on Saturday announced a joint partnership to develop and deploy "cutting-edge" underwater drone technologies as part of a push to boost maritime security. The announcement, which came during a security conference in Singapore, is part of a trilateral military alliance between the nations known as Aukus.