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Estimating spatially adjusted temperature-dependent time-varying reproduction numbers for vector-borne diseases

Estimating the effective reproduction number is crucial for understanding and managing infectious disease outbreaks. For vector-borne diseases like dengue, transmission depends on environmental and spatial conditions: temperature affects the extrinsic incubation period in mosquitoes, altering transmission timing, while spatial proximity can lead to clusters of transmission. We integrated a temperature-dependent (TD) generation time (GT) distribution and a spatial decay function weighting...

bioRxiv 6d ago