MUSCL
No mentions found
This entity hasn't been tracked yet, or Iris is still building its knowledge base.
Related Articles from SNS
Motion Tracking with Muscles: Predictive Control of a Parametric Musculoskeletal Canine Model
Announce Type: replace Abstract: We introduce a novel musculoskeletal model of a dog, procedurally generated from accurate 3D muscle meshes. Accompanying this model is a motion capture-based locomotion task compatible with a variety of control algorithms, as well as an improved muscle dynamics model designed to enhance convergence in differentiable control frameworks. We validate our approach by comparing simulated muscle activation patterns with experimentally obtained electromyography...
Comprehensive characterization of skeletal muscle remodeling in hSOD1G93A mice reveals limited functional impact of systemic FOXO1 inhibition
Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron (MN) loss, muscle atrophy and paralysis. Although traditionally considered a MN-specific disease, accumulating evidence supports a crucial contribution of skeletal muscle pathology to disease onset and progression. Except for specific mutations, to date there is no effective treatment for ALS.
Benzothiazole Derivatives as Dual Modulators of PGE2 and GABAergic Signaling in Skeletal Muscle
Benzothiazoles are attractive scaffolds for small-molecule modulators of neuronal signaling. However, their impact on skeletal muscle and GABAergic pathways remains poorly understood. We synthesized a focused library of benzothiazole derivatives via oxidative electrophilic substitution and profiled their activity in C2C12 skeletal muscle cells, assessing cytotoxicity, proliferation, myogenic differentiation, and GABA-related signaling using cell-based assays, real-time PCR, and transcriptomics.
Rebooting stem cells builds aged muscles and assists injury recovery
Muscle stem cells, which are crucial for building new muscle, don’t work as well as we get older, but giving them an artificial boost could rejuvenate them
Muscle-boosting drug could help retain lean tissue when using weight-loss jabs
The Independent's journalism is supported by our readers. When you purchase through links on our site, we may earn commission. Muscle-boosting drug could help retain lean tissue when using weight-loss jabs
Gait2Hip-60: A Unified Deep Learning Benchmark for Predicting Hip Muscle Forces and Joint Moments from Multi-Cadence Gait Kinematics
Announce Type: new Abstract: Estimating hip muscle forces and joint moments during gait typically relies on musculoskeletal simulation, which is informative but time-consuming and difficult to apply in clinical settings. This study developed a deep learning framework to predict these hip dynamics parameters directly from lower-limb gait kinematics and compared three representative sequence models under a unified protocol. Gait data were collected from 60 healthy adults under three...
Sim-to-Real Transfer for Muscle-Actuated Robots via Generalized Actuator Networks
arXiv:2604.09487v2 Announce Type: replace Abstract: Tendon drives paired with soft muscle actuation enable faster and safer robots while potentially accelerating skill acquisition. Still, these systems are rarely used in practice due to inherent nonlinearities, friction, and hysteresis, which complicate modeling and control. So far, these challenges have hindered policy transfer from simulation to real systems.
Muscle growth drug ‘could reduce loss of lean tissue’ when using slimming jabs
Trial suggests monoclonal antibody can help retain lean body mass when losing weight with GLP-1 medicinesA drug that promotes muscle growth could significantly reduce the loss of lean body mass when using slimming jabs, research suggests. While GLP-1 based jabs such as Wegovy and Mounjaro have proved highly effective at helping people who are overweight or obese, experts have warned it is not only fat that is lost. Studies suggest 25-40% of total weight loss is down to a reduction in lean...
Muscle growth drug ‘could reduce loss of lean tissue’ when using slimming jabs
Trial suggests monoclonal antibody can help retain lean body mass when losing weight with GLP-1 medicinesA drug that promotes muscle growth could significantly reduce the loss of lean body mass when using slimming jabs, research suggests. While GLP-1 based jabs such as Wegovy and Mounjaro have proved highly effective at helping people who are overweight or obese, experts have warned it is not only fat that is lost. Studies suggest 25-40% of total weight loss is down to a reduction in lean...
New drug to stop 'Ozempic butt' muscle loss
A third of the weight loss from obesity jabs can come from muscle, say experts.