Personal Development
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The survival horror game Hollowbody launches for PS5 and Xbox Series X/S on June 5
The well-received title was developed by a single person.
Genetic Scores are Booming. But Will Anti-Discrimination Laws Cover Your DNA?
A scanning electron micrograph of human chromosomes. Polygenic risk scoring, increasingly popular in personal medicine, uses an individual’s genome to estimate that person’s likelihood of developing a specific disease.
Genetic Scores are Booming. But Will Anti-Discrimination Laws Cover Your DNA?
A scanning electron micrograph of human chromosomes. Polygenic risk scoring, increasingly popular in personal medicine, uses an individual’s genome to estimate that person’s likelihood of developing a specific disease.
Ask HN: What is your (AI) dev tech stack / workflow? (June 2026)
Hello, happy Friday!I am looking to do some in-person "developer boot-up" workshops, and seek your suggestions for "modern tooling". The background of the participants range from motivated newbie ("I heard you can make your own app with AI!") to existing software developers who want to get up to speed on modern development for the purposes of building stuff, and getting jobs where AI tools are being used. For those who have been doing software development & "tech" lately using AI tools, and...
RPO-PDT: Demonstrating Role-Play-Based Knowledge Adaptation for Student Support Dialogue (Demonstration System)
arXiv:2606.09255v1 Announce Type: new Abstract: We present RPO-PDT: a retrieval-grounded, role-play-based dialogue system for adaptive student support in higher education. RPO-PDT is: (1) able to provide institution-specific Personal Development Tutor (PDT) guidance using structured knowledge sources; (2) constrained by explicit persona, boundary, confidentiality, and safety policies; and (3) designed around a reverse-roleplay loop where unresolved interactions are replayed from the student...
Tencent’s chief AI scientist dismisses lag concerns, says race a ‘long-term game’
Yao Shunyu, the former OpenAI researcher now leading Tencent Holdings’ artificial intelligence model development, pushed back against concerns that the tech giant is slow in AI, arguing that the race is just beginning with massive untapped opportunities in coding agents and embodied intelligence. “AI is a long-term game, with the second half of the race just starting,” said Yao, chief AI scientist at Tencent, comparing the current state to the development of personal computers in the 1970s.
Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes
Cancer genome analysis relies on standard human reference genomes but detecting somatic alterations in highly repetitive or individual-specific regions remains challenging. We developed the Personalized Reference genome-based Cancer Genome Analysis Pipeline (PRCGAP), to our knowledge, the first comprehensive pipeline integrating haplotype-resolved analyses of somatic point mutations, structural variants, copy number, and DNA methylation on personalized diploid reference genomes. We applied...
MCP-Persona: Benchmarking LLM Agents on Real-World Personal Applications via Environment Simulation
arXiv:2606.02470v1 Announce Type: new Abstract: The Model Context Protocol (MCP) has emerged as a transformative standard for connecting large language models (LLMs) with external data sources and tools, and has been rapidly adopted across personal applications and development platforms. However, existing benchmarks predominantly focus on generic information-seeking tools and fail to capture the practical challenges posed by personal social applications, where tools interact with individual...
SocialCoach: Personalized Social Skill Learning with RL-based Agentic Tutoring and Practice
arXiv:2606.04155v1 Announce Type: new Abstract: Social skills such as negotiation and leadership are crucial for personal and professional success in today's interconnected world. However, scalable and effective training remains a significant challenge due to the scarcity of expert coaching. In this paper, we introduce SocialCoach, a holistic LLM-powered agentic tutoring system for personalized social skill development at scale.
LLMs + Persona-Plug = Personalized LLMs
arXiv:2409.11901v2 Announce Type: replace Abstract: Personalization plays a critical role in numerous language tasks and applications, since users with the same requirements may prefer diverse outputs based on their individual interests. This has led to the development of various personalized approaches aimed at adapting large language models (LLMs) to generate customized outputs aligned with user preferences. Some of them involve fine-tuning a unique personalized LLM for each user, which is...