Science
Screen reveals new proteins that control RNA processing
Key Points
Researchers at the University of California San Diego have developed a large-scale screening approach that identifies proteins controlling a fundamental step in gene expression known as alternative polyadenylation (APA). APA determines where an RNA molecule is cut and finished before it is translated into protein, influencing the stability, localization and function of thousands of genes. The paper is published in the journal Molecular Cell.
Researchers at the University of California San Diego have developed a large-scale screening approach that identifies proteins controlling a fundamental step in gene expression known as alternative polyadenylation (APA). APA determines where an RNA molecule is cut and finished before it is translated into protein, influencing the stability, localization and function of thousands of genes. The paper is published in the journal Molecular Cell.