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Organ on chip model of respiratory vascular interactions under COPD relevant oxidative stress

Oxidative stress-induced airway injury contributes to chronic obstructive pulmonary disease (COPD). Cardiovascular complications increase COPD morbidity and mortality, but mechanistic links between airway injury and vascular dysfunction remain unclear, largely due to limitations of in vitro models that fail to replicate the multicellular lung environment. We developed REVAS, a modular organ-on-chip platform to study human respiratory-vascular cell-cell interactions at baseline and under...

bioRxiv 1d ago

Bugs and black mold: What some mobile home park residents see after investors buy in

This article is part of “Unaffordable America,” a series examining rising economic inequality in the U.S. and the policies that drive it. Soon after Aliea Brown rented Unit 62 at the Buck Island Manufactured Home Community in northern Mississippi in 2023, it became clear she couldn’t stay. The front door was hung upside down, Brown said, black mold began growing throughout the unit and the windows weren’t sealed properly.

NBC News 7h ago

NHS issues 'thunderstorm' alert to 7.2m people across UK

NHS issues 'thunderstorm' alert to 7.2m people across UK People have been warned that they could face a 'triple threat' during certain weather conditions This week, the British heatwave gives way to wet, rainy conditions, with the chance of thunder in parts of the UK. This has prompted millions to receive a health alert about how this may affect some people who have trouble breathing. In a post on Instagram, the NHS said: "Thunderstorms can trigger symptoms for those with lung conditions,...

Daily Mirror 9d ago