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Multiscale Fourier Neural Operator for Inverse Wave Scattering in Highly Oscillatory Media

Announce Type: new Abstract: In this paper, we propose an operator learning method based on the multiscale Fourier neural operator (MscaleFNO) for inverse medium problems of Helmholtz equations. The MscaleFNO provides a neural surrogate model with reduced spectral bias for the Helmholtz equations, mapping highly oscillatory medium profiles to scattered wavefields. A plug-and-play inversion using elucidated diffusion model is introduced to regularize the inverse solver based on least squares...

arXiv CS 1d ago

TabSODA: Tabular Diffusion based Imputation with Skip Pattern Detection and Ordinal Awareness

arXiv:2606.05361v1 Announce Type: cross Abstract: Missing data imputation in large-scale surveys faces two challenges that are not well handled by current tabular diffusion methods. First, \emph{structural skips}, cells made inapplicable by questionnaire design, should not be imputed but are often conflated with item nonresponse. Second, \emph{ordinal} responses encode ordered categories, yet most pipelines treat them as nominal levels through one-hot or analog-bit encodings.

arXiv CS 5d ago

A prognostic human brain network for diffuse midline glioma

Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.

Nature 17h ago

Drift-Diffusion Matching: Embedding dynamics in latent manifolds of asymmetric neural networks

arXiv:2602.14885v2 Announce Type: replace-cross Abstract: Recurrent neural networks (RNNs) provide a theoretical framework for understanding computation in biological neural circuits, yet classical results, such as Hopfield's model of associative memory, rely on symmetric connectivity that restricts network dynamics to gradient-like flows. In contrast, biological networks support rich time-dependent behaviour facilitated by their asymmetry. Here we introduce a general framework, which we...

arXiv CS 6d ago

Structural basis for chaperone-guided assembly of RNA-induced silencing complex

Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).

Nature 17h ago

Whole-genome duplication shaped cell-type evolution in the vertebrate brain

Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...

Nature 17h ago