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Mitochondria directly interact with the nuclear pore complex

Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.

Nature 1d ago

Health screening in Singapore: A more proactive approach to preventive care

Health screening in Singapore: A more proactive approach to preventive care Protocol combines comprehensive blood screening, doctor consultations and health coaching to help patients better understand their health risks and act earlier. At 17, Mr Mehdi Elaichouni was diagnosed with Crohn’s disease, a chronic inflammatory condition affecting the intestinal tract. While treatment helped manage acute flare-ups, he felt his care focused mainly on symptoms.

Channel News Asia 3h ago

100 days into Iran war: How rising costs are hitting consumers and businesses in Southeast Asia

100 days into Iran war: How rising costs are hitting consumers and businesses in Southeast Asia As the war on Iran marks its 100th day on Monday (Jun 8), CNA looks at how the geopolitical crisis is filtering into everyday life across the region. SINGAPORE: More than three months into the war on Iran, the aftershocks from disrupted Middle Eastern energy and shipping routes are being felt far beyond the oil market, from road construction sites in Malaysia to food and beverage operators in...

Channel News Asia 4d ago

'Not going to vacate': Rabri's 'evict by force' dare to CM Samrat over bungalow

Former Bihar chief minister Rabri Devi on Saturday challenged chief minister Samrat Choudhary to remove her from the government bungalow she has occupied for more than a decade, saying she would not vacate the premises voluntarily. The RJD leader reacted sharply when reporters questioned her about a recent order issued by the state's building construction department allotting the 10, Circular Road residence in Patna to Dairy and Fisheries Minister Nand Kishor Ram. "Yes, I can see that Samrat...

Times of India 11d ago

Malaysia’s LGBTQ groups tread more carefully amid recent enforcement, ministers’ rhetoric

Malaysia’s LGBTQ groups tread more carefully amid recent enforcement, ministers’ rhetoric Recent moves by the Malaysian authorities point to a more restrictive climate for LGBTQ people in the country, analysts say, and this could be due to political competition as well as the visibility of some events. SINGAPORE: The blocking of two same-sex dating websites; a deputy minister urging Malaysians to use the term “deviant culture” to refer to the LGBTQ (lesbian, gay, bisexual, transgender or...

Channel News Asia 11d ago